Is there a link between galactic cosmic rays and clouds? The CLOUD experiment at CERN Urs Baltensperger Laboratory of Atmospheric Chemistry, Paul Scherrer Institut, 5232 Villigen PSI, Switzerland Globally, a significant source of cloud condensation nuclei for cloud formation is thought to originate from new particle formation (aerosol nucleation). Despite an extensive research effort, many questions remain about the dominant nucleation mechanisms. The potential influence of ions from galactic cosmic rays on the atmospheric aerosol nucleation processes may play an important role relevant for aerosol production, cloud formation and climate. Variability of galactic cosmic rays due to modulating influences from the sun therefore may affect (regional) climate on various time scales. Similarly, a quantitative understanding of the dependence of the nucleation rate on the concentration of the nucleating substances such as gaseous sulfuric acid, ammonia, water vapor and others has not been reached. This is of relevance for climate as the atmospheric concentrations of sulfuric acid, ammonia and other nucleating agents are strongly influenced by anthropogenic emissions. In this presentation first an overview is given of the potential processes by which cosmic rays may affect climate and examples of the correlations of atmospheric and paleo-climatic parameters suggesting this connection are briefly reviewed. Then, the first results from the CLOUD experiment in the new aerosol chamber facility at CERN are presented, which recently have been published in Nature (Kirkby et al., 2011). Kirkby J. et al. (2011) Role of sulphuric acid, ammonia and galactic cosmic rays in atmospheric aerosol nucleation. Nature, 476, 429-433, doi: 10.1038/nature10343